Diabetes┬áis often called the “silent killer” because it attacks the body slowly and stealthily. Newly diagnosed adult diabetes patients are usually not overly concerned about it since their symptoms are often no more serious than frequent urination and increased thirst. Many other patients have no symptoms at all.

However, as time goes by, the consequences of both types of diabetes become increasingly serious and can lead to death. These include heart disease, eye problems, kidney failure, nerve damage and erectile dysfunction, to name a few. Major contributors to the degenerative effects of diabetes are hyperglycemia (high blood sugar) and hypoglycemic events (acute low blood sugar). Recent studies suggest that even some oral diabetes medications contribute to heart failure. Thus, it is critical that men and women who are diagnosed with diabetes seek treatment to reduce hyperglycemia and hypoglycemic events that will, in time, trigger these dangerous, degenerative conditions.

Our innovative, autologous (originating from your own body) stem cell therapy for diabetes I and II does just that – drug free. It fights diabetes at its roots, reducing hyperglycemia and its associated complications (see above). Recent evidence suggests that it also reduces hypoglycemic (low blood sugar) events that can result in death if not treated promptly.

The A1 Medical Center Diabetes Stem Cell Treatment

Diabetes patients are usually treated by injecting the stem cells into the pancreatic artery via catheter. Patients who cannot safely undergo the catheterization procedure may elect to receive the stem cells intravenously.

Both methods are outpatient procedures that require patients to stay 4 or 5 nights.

Diagnostics and Physical Assessment

Before stem cell implantation, each patient undergoes blood tests at the clinic.

Step 1 – Bone Marrow Collection

Bone marrow is collected from the patient’s iliac crest (hip bone) using thin-needle mini-puncture under local anesthesia. Although some pain is felt when the needle is inserted, most patients do not find the bone marrow collection procedure particularly painful. The entire procedure normally takes about 30 minutes.

Once the bone marrow collection is complete, the patient may return to their hotel and go about normal activities.

More detailed information on the bone marrow collection procedure is available in the Bone Marrow Informed Consent document (PDF file).

Step 2 – Laboratory Processing

The stem cells are processed from the bone marrow in a state-of-the-art, government approved (cGMP) laboratory. In the lab, both the quantity and quality of the stem cells are measured. These cells have the potential to transform into multiple types of cells and are capable of regenerating damaged cells such as pancreatic beta cells.

Step 3 – Stem Cell Implantation

The stem cells are implanted into the pancreatic artery under local anesthesia using a fine wire (catheter) that is inserted into the patient’s right femoral artery. X-ray scanning is used to guide the catheter into the pancreatic artery where the stem cells are injected through a small hole in the center of the wire. This procedure takes about 90 minutes. Afterwards, the patient will spend 2 or 3 hours in the recovery room to ensure that the entry site is not bleeding.

More detailed information about the catheterization (angiography) procedure may be found in the Angiography Informed Consent document (PDF file).

Patients who cannot be treated by catheter, such as those with kidney problems, are offered an alternative intravenous stem cell implantation.

Patients who are suffering from diabetic peripheral neuropathy will receive a portion of their stem cells via intramuscular injections into the leg muscles.

Following Treatment

Patients are required to stay in town on the fourth day for general safety considerations. They may return home on the fifth day.

Diabetes Stem Cell Therapy Results

131 patients were evaluated. Diabetes type I patients (N=23 / left bar) reported more stable blood glucose (35,3%) and less hypoglycemia (36,7%). Diabetes type II patients (N=33 / right bar) also reported more stable blood glucose (51,0%) and less neuropathic symptoms, such as less numbness (42,4%) and more feeling in the legs (44,1%).

In the group that send their post treatment period laboratory results (N=71) the HbA1c values decreased after different follow up periods in both type I and type II diabetes patients. In type I patients (N=28), the highest decrease of HbA1c value was seen between 3 and 6 months after treatment, which corresponds with the first 3 months after treatment. The highest decrease of the HbA1c value in type 2 patients (N=43) was seen 6 months and beyond after treatment, which suggests a longer lasting effect of stem cell treatment. Furthermore, 38 patients reported a decrease in medication, with more than 60% reduction in DM type II patients (N=23) and 30% reduction in DM type I patients (N=15).

Follow up statistics from 50 diabetes patients show that more than 50% experienced improvements after stem cell therapy.

40% of the patients were insulin dependent (type 1) and 60% were non-insulin dependent (type 2). About 4 of 5 patients were male and the average age was 51 years old.

Approximately 1/3 of insulin dependent patients improved following treatment while about 2/3 of non-insulin dependent patients improved.

Overall, improvements reported included more stable blood glucose levels, lower fasting blood glucose levels, decreased leg pain, lower blood pressure and the elimination of hypoglycemic episodes. Nearly 1 in 4 male patients regained erectile function.


Patient Stories

Read what our patients have to say about their treatment:

Sean DePaula, 20 years old, Diabetes Type 1

“My insulin needs have dropped dramatically…”

Dr. Prof. Alberto Bazzan, 64 years old, Diabetes Type 2

“For the past 10 weeks, I have stopped taking metformin altogether!…”

Treatment Evaluation Process

In order to be evaluated for stem cell treatment, patients must complete an online medical history form. Once you’ve completed the online medical history and submitted it, a patient relations consultant will contact you. He or she will assist you with the rest of the evaluation process. Upon treatment approval, your consultant will also assist you with treatment scheduling and trip preparation.